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Metabolism


Metabolism is the set of life-sustaining chemical transformations within the cells of living organisms. The three main purposes of metabolism are the conversion of food/fuel to energy to run cellular processes, the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates, and the elimination of nitrogenous wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. 

  • Fludarabine EY0005

    Fludarabine, a purine analog, is used in the treatment of hematological malignancies for the inhibition of STAT-1 activation and DNA synthesis. Fludarabine是一种STAT1活性抑制剂和DNA合成抑制剂。

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  • Cucurbitacin I EY2197

    Selective inhibitor of STAT3/JAK2 signaling. Inhibits the activation of STAT3 and JAK2 and displays no activity on Src, Akt, ERK and JNK. Suppresses phosphotyrosine levels of STAT3, inhibits STAT3 DNA binding and STAT3-mediated gene expression. Induces apoptosis in cell lines expressing constitutively active tyrosine-phosphorylated STAT3.

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  • Skepinone-L EY1855

    Skepinone-L是一种选择性p38 MAPK抑制剂,IC50为5 nM。

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  • Aripiprazole EY1816

    Aripiprazole是一种人5-HT1A受体激动剂,Ki为4.2 nM。

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  • Palonosetron HCl EY1800

    Palonosetron是5-HT3拮抗剂,能抑制化疗引起的恶心呕吐(CINV)。

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