VEGFR


VEGF receptors are receptors for vascular endothelial growth factor (VEGF).  There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.Vascular endothelial growth factor (VEGF) is an important signaling protein involved in both vasculogenesis (the formation of the circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF also enhances microvascular permeability and is sometimes referred to as vascular permeability factor.
  • DMH4 EI1009

    DMH4是选择性 VEGFR-2 抑制剂。

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  • (Z)-FeCP-oxindole EI0167

    (Z)-FeCP-oxindole是选择性 VEGFR-2 抑制剂。

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  • (E)-FeCP-oxindole EI0110

    (E)-FeCP-oxindole是选择性 VEGFR-2 抑制剂。

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  • Vatalanib succinate EI2878

    Vatalanib succinate是活性的 VEGFR 抑制剂, 也是aromatase的抑制剂。

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  • Toceranib EI2794

    Toceranib是活性的PDGFR,VEGFR抑制剂。

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  • DMH4 EI1009

    DMH4是选择性 VEGFR-2 抑制剂。

    More
  • (Z)-FeCP-oxindole EI0167

    (Z)-FeCP-oxindole是选择性 VEGFR-2 抑制剂。

    More
  • (E)-FeCP-oxindole EI0110

    (E)-FeCP-oxindole是选择性 VEGFR-2 抑制剂。

    More
  • Vatalanib succinate EI2878

    Vatalanib succinate是活性的 VEGFR 抑制剂, 也是aromatase的抑制剂。

    More
  • Toceranib EI2794

    Toceranib是活性的PDGFR,VEGFR抑制剂。

    More
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