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Rac


Rac is a member of the RAS superfamily of small GTPase. It functions in various cellular processes including regulation of secretory processes, membrane ruffles, cell polarization and phagocytosis of apoptotic cells etc. It is contributed to malignant progression.

  • CPYPP EI0875

    CPYPP是DOCK2-Rac1 interaction inhibitor.。

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  • EHop-016 EY1818

    EHop-016是Rac GTPase高效选择性抑制剂，在MDA-MB-435细胞中IC50值1.1uM。

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  • NSC 23766 EY1455

    NSC 23766是一种RacGTPase抑制剂，通过鸟嘌呤核苷酸交换因子（GEFs），靶向激活Rac，IC50为50 μM。但不抑制与其相关的靶点Cdc42和RhoA。

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  • EHT 1864 EY1147

    EHT 1864是Rac1信号转导抑制剂，能调节γ-分泌酶介导的APP。

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