GSK-3


GSK-3 (Glycogen synthase kinase 3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues.Phosphorylation of a protein by GSK-3 usually inhibits the activity of its downstream target. GSK-3 is active in a number of central intracellular signaling pathways, including cellular proliferation, migration, glucose regulation, and apoptosis. In mammals GSK-3 is encoded by two known genes, GSK-3 alpha (GSK3A) and GSK-3 beta (GSK3B). 
  • GSK J2 EI1249

    GSK J2是GSK J1的非活性异构体。

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  • GSK J5 EI1250

    GSK J5是GSK J4的非活性异构体,具有细胞膜通透性。

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  • BIO-acetoxime EI0581

    BIO-acetoxime是选择性 GSK-3α/β 抑制剂。

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  • A 1070722 EI0322

    A 1070722是高 活性的, 选择性 GSK-3 抑制剂。

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  • TWS 119 EI2825

    TWS 119是GSK-3β 抑制剂, induces neuronal differentiation in ESCs。

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  • GSK J2 EI1249

    GSK J2是GSK J1的非活性异构体。

    More
  • GSK J5 EI1250

    GSK J5是GSK J4的非活性异构体,具有细胞膜通透性。

    More
  • BIO-acetoxime EI0581

    BIO-acetoxime是选择性 GSK-3α/β 抑制剂。

    More
  • A 1070722 EI0322

    A 1070722是高 活性的, 选择性 GSK-3 抑制剂。

    More
  • TWS 119 EI2825

    TWS 119是GSK-3β 抑制剂, induces neuronal differentiation in ESCs。

    More
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