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LPA Receptor


LPARs (lysophosphatidic acid receptors) are a group of G protein-coupled receptors for lysophosphatidic acid (LPA) that include:
Lysophosphatidic acid receptor 1 (LPAR1; formerly known as EDG2, GPR26)
Lysophosphatidic acid receptor 2 (LPAR2; formerly known as EDG4)
Lysophosphatidic acid receptor 3 (LPAR3; formerly known as EDG7)
Lysophosphatidic acid receptor 4 (LPAR4; formerly known as GPR23, P2RY9)
Lysophosphatidic acid receptor 5 (LPAR5; formerly known as GPR92)
Lysophosphatidic acid receptor 6 (LPAR6; formerly known as GPR87, P2RY5).
  • AM966 EY2827

    AM966是高亲和性的口服的溶血磷脂酸(LPA1)受体拮抗剂(IC50=17 nM),比对其它LPA受体的抑制性高。

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  • H2L 5765834 EI1275

    H2L 5765834是LPA1,3,5 拮抗剂。

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  • H2L5186303 EI1276

    H2L5186303是活性的,选择性 LPA2 受体拮抗剂。

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  • GRI 977143 EI1230

    GRI 977143是选择性 LPA2 受体 非lipid 激动剂。

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  • 1-Oleoyl lysophosphatidic acid sodium salt EI0226

    1-Oleoyl lysophosphatidic acid sodium salt是LPA1 和 LPA2的内源性激动剂。

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