NMDAR
NMDAR(N-methyl-D-aspartate receptor) is a glutamate receptor and ion channel protein found in nerve cells. It is activated when glutamate and glycine (or D-serine) bind to it, and when activated it allows positively charged ions to flow through the cell membrane. The NMDA receptor is very important for controlling synaptic plasticity and memory function. The NMDAR is a specific type of ionotropic glutamate receptor.
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Felbamate (Felbatol,FBM) is an anticonvulsant drug used in the treatment of epilepsy.
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Ibotenic acid是非选择性 NMDA 激动剂。
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Homoquinolinic acid是选择性, 活性的 NMDA 激动剂。
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HU 211是NMDA 受体拮抗剂, 也是NF-κB 抑制剂。
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Eliprodil是非竞争性 NR2B-选择性 NMDA 拮抗剂。
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