SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
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GR 159897是非肽类的活性NK2拮抗剂。
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FTIDC是mGlu1活性选择性阴性变构的调节剂（negative allosteric modulator），也是mGlu1 反向激动剂。
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FK 888是高亲和性 NK1 受体拮抗剂。
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Fenobam是活性选择性 mGlu5 拮抗剂。
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EGLU是高选择性 group II mGlu 拮抗剂。
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GR 159897是非肽类的活性NK2拮抗剂。
More
-
FTIDC是mGlu1活性选择性阴性变构的调节剂（negative allosteric modulator），也是mGlu1 反向激动剂。
More
-
FK 888是高亲和性 NK1 受体拮抗剂。
More
-
Fenobam是活性选择性 mGlu5 拮抗剂。
More
-
EGLU是高选择性 group II mGlu 拮抗剂。
More
-
GR 159897是非肽类的活性NK2拮抗剂。
More
-
FTIDC是mGlu1活性选择性阴性变构的调节剂（negative allosteric modulator），也是mGlu1 反向激动剂。
More
-
FK 888是高亲和性 NK1 受体拮抗剂。
More
-
Fenobam是活性选择性 mGlu5 拮抗剂。
More
-
EGLU是高选择性 group II mGlu 拮抗剂。
More
