AhR
AhR (The aryl hydrocarbon receptor) is a protein that in humans is encoded by the AHR gene. AhR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic (aryl) hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AhR is a member of the family of basic helix-loop-helix transcription factors. AHR binds several exogenous ligands such as natural plant flavonoids, polyphenolics and indoles, as well as synthetic polycyclic aromatic hydrocarbons and dioxin-like compounds. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones.
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StemRegenin 1 (SR1), a purine derivative, is a high affinity antagonist of the aryl hydrocarbon receptor (AhR) transcription factor that expands CD34+ cells. StemRegenin 1(SR1)是芳香烃受体（AhR）拮抗剂，能促进人CD34+外周血和脐带血造血干细胞（HSC）的自我更新。
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FICZ(6-Formylindolo[3,2-b]carbazole)是芳香烃受体AHR配体，CYP1A1基因表达的有效诱导剂。
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CH-223191是选择性AhR受体拮抗剂。
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UM729是一种新型的嘧啶吲哚，对AhR拮抗剂有协同效应，能抑制AML细胞的分化。
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