Kinesin
A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells.
Kinesins move along microtubule (MT) filaments, and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport. Most kinesins walk towards the positive end of a microtubule, which, in most cells, entails transporting cargo such as protein and membrane components from the centre of the cell towards the periphery. This form of transport is known as anterograde transport. In contrast, dyneins are motor proteins that move toward the microtubules' negative end.
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Dimethylenastron是Mitotic motor kinesin Eg5的抑制剂。
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BRD 9876是ATP 非竞争性 kinesin Eg5 抑制剂。
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ARRY 520 trifluoroacetate是活性的,选择性 kinesin spindle protein (KSP) 抑制剂, 诱导 Mcl-1 降解。
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S-Trityl-L-cysteine是Mitotic kinesin Eg5的活性的选择性的抑制剂。
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Monastrol是Mitotic kinesin Eg5 选择性抑制剂。
More
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Dimethylenastron是Mitotic motor kinesin Eg5的抑制剂。
More
-
BRD 9876是ATP 非竞争性 kinesin Eg5 抑制剂。
More
-
ARRY 520 trifluoroacetate是活性的,选择性 kinesin spindle protein (KSP) 抑制剂, 诱导 Mcl-1 降解。
More
-
S-Trityl-L-cysteine是Mitotic kinesin Eg5的活性的选择性的抑制剂。
More
-
Monastrol是Mitotic kinesin Eg5 选择性抑制剂。
More