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EGFR


The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

  • Varlitinib EY2424

    ARRY334543 is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.

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  • HKI 357 EI1299

    HKI 357是ErbB2和EGFR双重不可逆的抑制剂。

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  • GW 583340 dihydrochloride EI1263

    GW 583340 dihydrochloride是活性的双效EGFR/ErbB2抑制剂， 口服有效。

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  • CGP 52411 EI0753

    CGP 52411是EGFR 抑制剂。 也抑制 Aβ42 原纤成形。

    More

  • BIBX 1382 dihydrochloride EI0573

    BIBX 1382 dihydrochloride是高选择性 EGFR-激酶抑制剂。

    More

  • Varlitinib EY2424

    ARRY334543 is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.

    More

  • HKI 357 EI1299

    HKI 357是ErbB2和EGFR双重不可逆的抑制剂。

    More

  • GW 583340 dihydrochloride EI1263

    GW 583340 dihydrochloride是活性的双效EGFR/ErbB2抑制剂， 口服有效。

    More

  • CGP 52411 EI0753

    CGP 52411是EGFR 抑制剂。 也抑制 Aβ42 原纤成形。

    More

  • BIBX 1382 dihydrochloride EI0573

    BIBX 1382 dihydrochloride是高选择性 EGFR-激酶抑制剂。

    More

  • Varlitinib EY2424

    ARRY334543 is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.

    More

  • HKI 357 EI1299

    HKI 357是ErbB2和EGFR双重不可逆的抑制剂。

    More

  • GW 583340 dihydrochloride EI1263

    GW 583340 dihydrochloride是活性的双效EGFR/ErbB2抑制剂， 口服有效。

    More

  • CGP 52411 EI0753

    CGP 52411是EGFR 抑制剂。 也抑制 Aβ42 原纤成形。

    More

  • BIBX 1382 dihydrochloride EI0573

    BIBX 1382 dihydrochloride是高选择性 EGFR-激酶抑制剂。

    More
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