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Dopamine Receptor


Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors.  There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family. 
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  • Nefopam HCl EY2803

    Nefopam is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain.

    More
  • Fenoldopam (mesylate) EY2707

    Fenoldopam mesylate is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist. Fenoldopam Mesylate is an anti-hypertensive, dopamine D1-receptor agonist.

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  • Rotigotine EY2583

    Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.

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  • Azaperone EY2567

    Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

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  • Penfluridol EY2531

    Penfluridol is a highly potent, first generation diphenylbutylpiperidine antipsychotic.

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