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Glucocorticoid Receptor


The glucocorticoid receptor (GR,GCR,NR3C1) is the receptor to which cortisol and other glucocorticoids bind.The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. The GR is abnormal in familial glucocorticoid resistance.
In central nervous system structures, the glucocorticoid receptor is gaining interest as a novel representative of neuroendocrine integration, functioning as a major component of endocrine influence - specifically the stress response - upon the brain.
  • Cortisone acetate EY2854

    Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.

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  • Prednisolone Acetate EY2858

    Prednisolone Acetate is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.

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  • Ciclesonide EY2726

    Ciclesonide is a corticosteroid pro-drug of des-ciclesonide, which has shown to have anti-inflammatory activity with affinity for glucocorticoid receptors.

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  • Flumethasone EY2509

    Flumethasone is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.

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  • Fluocinonide EY2420

    Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.

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  • Cortisone acetate EY2854

    Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.

    More
  • Prednisolone Acetate EY2858

    Prednisolone Acetate is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.

    More
  • Ciclesonide EY2726

    Ciclesonide is a corticosteroid pro-drug of des-ciclesonide, which has shown to have anti-inflammatory activity with affinity for glucocorticoid receptors.

    More
  • Flumethasone EY2509

    Flumethasone is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.

    More
  • Fluocinonide EY2420

    Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.

    More
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