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Oct-4


Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.

  • OAC1 EY0349

    OAC1是转录因子Oct4活化剂，提高iPSC的重编程效率和编程过程中的加速。

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  • OAC1 EY0349

    OAC1是转录因子Oct4活化剂，提高iPSC的重编程效率和编程过程中的加速。

    More
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