PDGFR
PDGF-R(Platelet-derived growth factor receptors) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. PDGF subunits -A and -B are important factors regulating cell proliferation, cellular differentiation, cell growth, development and many diseases including cancer. There are two forms of the PDGF-R, alpha and beta each encoded by a different gene. Depending on which growth factor is bound, PDGF-R homo- or heterodimerizes.
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DMPQ dihydrochloride是PDGFRβ活性选择性抑制剂。
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AC 710是活性的，选择性 PDGFR 家族抑制剂。
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Toceranib是活性的PDGFR，VEGFR抑制剂。
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SU 16f是活性选择性的 PDGFRβ 抑制剂。
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PD 166285 dihydrochloride是活性的 Src 抑制剂， 也能抑制 FGFR1， PDGFRβ 和 Wee1。
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DMPQ dihydrochloride是PDGFRβ活性选择性抑制剂。
More
-
AC 710是活性的，选择性 PDGFR 家族抑制剂。
More
-
Toceranib是活性的PDGFR，VEGFR抑制剂。
More
-
SU 16f是活性选择性的 PDGFRβ 抑制剂。
More
-
PD 166285 dihydrochloride是活性的 Src 抑制剂， 也能抑制 FGFR1， PDGFRβ 和 Wee1。
More
