CRM1


CRM1 (chromosomal maintenance 1,Exportin 1 (XPO1)) is an eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA. Exportin 1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
  • IDRA 21 EI1335

    IDRA 21是抑制 AMPA 受体脱敏(inhibit desensitization)。

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  • IEM 1460 EI1336

    IEM 1460是IEM 1460 is an AMPA currents' open-channel blocker and selective for non-GluR2-containing receptors.。

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  • GYKI 47261 dihydrochloride EI1270

    GYKI 47261 dihydrochloride是非竞争性 AMPA 拮抗剂。

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  • GYKI 52466 dihydrochloride EI1271

    GYKI 52466 dihydrochloride是选择性非竞争性AMPA拮抗剂。

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  • GYKI 53655 hydrochloride EI1272

    GYKI 53655 hydrochloride是非竞争性AMPA受体拮抗剂。

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