Sodium Channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("Voltage-gated", "voltage-sensitive", or "voltage-dependent" sodium channel also called "VGSCs" or "Nav channel") or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials.
-
D-I03 is a selective inhibitor of RAD52 with a Kd value of 25.8 µM.
D-I03 inhibits ssDNA annealing via RAD52 and D-loop formation, with IC50 values of 5 µM and 8 µM, respectively.
More
-
RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with an IC₅₀ of 5 to 30 µM.
More
-
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
More
-
Azelastine hydrochloride (Astelin) is a potent, second-generation, selective, histamine antagonist.
More
-
Pemirolast Potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
More
