Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice). This homolog is crucial in multicellular organisms, where it prevents cancer formation, thus, functions as a tumor suppressor. p53 has many mechanisms of anticancer function and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. 
  • HLI 373 EI1300

    HLI 373是Hdm2 抑制剂,激活p53-dependent transcription。

  • CP 31398 dihydrochloride EI0857

    CP 31398 dihydrochloride是p53稳定剂。

  • SJ 172550 EI2562

    SJ 172550是MDMX 抑制剂。 扰乱 MDMX-p53 之间的相互作用。。

  • SCH 529074 EI2512

    SCH 529074是SCH 529074 restores mutant p53 activity。

  • RETRA hydrochloride EI2324

    RETRA hydrochloride是抗肿瘤活性,可以抑制 mutant p53-bearing 肿瘤细胞。

  • Current page1, Total Pages4, Total Record19 First Prev 1234 Next Last Goto