FLT3
FLT3 (fms like tyrosine kinase 3,Cluster of differentiation antigen 135 (CD135) ,fetal liver kinase-2 (Flk2)) is a protein that is a cytokine receptor which belongs to the receptor tyrosine kinase class III. FLT3 is the receptor for the cytokine Flt3 ligand (FLT3L). It is expressed on the surface of many hematopoietic progenitor cells. Signalling of FLT3 is important for the normal development of haematopoietic stem cells and progenitor cells. Signaling through FLT3 plays a role in cell survival, proliferation, and differentiation.
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CHMFL-FLT3-122是活性的，选择性 FLT3 抑制剂。
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5'-Fluoroindirubinoxime是FLT3 抑制剂， antiproliferative activity。
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TCS 359是活性FLT3抑制剂。
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Lestaurtinib是JAK2， FLT3，TrkA 抑制剂。
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KG 5是PDGFRβ， B-Raf， c-Raf， FLT3，KIT 的抑制剂。
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