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Caspase


Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation.These forms of cell death are important for protecting an organism from stress signals and pathogenic attack. These are signalling molecules that allow recruitment of immune cells to an infected cell or tissue. There are other identified roles of caspases such as cell proliferation, tumour suppression, cell differentiation, neural development and axon guidance and ageing.
  • Z-VAD(OH)-FMK EY2820

    Z-VAD-FMK是一类不可逆的泛caspase抑制剂。

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  • AZ 10417808 EI0511

    AZ 10417808是选择性非肽类caspase-3 抑制剂。

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  • PETCM EI2115

    PETCM是Caspase-3的激动剂。

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  • Z-VAD-FMK EY1607

    Z-VAD-FMK是一种可渗透细胞的,不可逆的pan-caspase抑制剂,能够抑制细胞凋亡。

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  • Belnacasan EY1555

    VX-765 is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM.

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  • Z-VAD(OH)-FMK EY2820

    Z-VAD-FMK是一类不可逆的泛caspase抑制剂。

    More
  • AZ 10417808 EI0511

    AZ 10417808是选择性非肽类caspase-3 抑制剂。

    More
  • PETCM EI2115

    PETCM是Caspase-3的激动剂。

    More
  • Z-VAD-FMK EY1607

    Z-VAD-FMK是一种可渗透细胞的,不可逆的pan-caspase抑制剂,能够抑制细胞凋亡。

    More
  • Belnacasan EY1555

    VX-765 is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM.

    More
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