NF-κB
NF-κB is important in regulating cellular responses because it belongs to the category of "rapid-acting" primary transcription factors, i.e., transcription factors that are present in cells in an inactive state and do not require new protein synthesis in order to become activated (other members of this family include transcription factors such as c-Jun, STATs, and nuclear hormone receptors). This allows NF-κB to be a first responder to harmful cellular stimuli. Known inducers of NF-κB activity are highly variable and include reactive oxygen species (ROS), tumor necrosis factor alpha (TNFα), interleukin 1-beta (IL-1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaine, and ionizing radiation.
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Sodium salicylate is used in medicine as an analgesic and antipyretic.
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HU 211是NMDA 受体拮抗剂， 也是NF-κB 抑制剂。
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CID 2858522是选择性抑制 PKC诱导的 NF-κB 激活。
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Cardamonin是NF-κB activation的抑制剂， 抗炎症活性。
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Bengamide B是NF-κB 激活的高活性抑制剂。
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Sodium salicylate is used in medicine as an analgesic and antipyretic.
More
-
HU 211是NMDA 受体拮抗剂， 也是NF-κB 抑制剂。
More
-
CID 2858522是选择性抑制 PKC诱导的 NF-κB 激活。
More
-
Cardamonin是NF-κB activation的抑制剂， 抗炎症活性。
More
-
Bengamide B是NF-κB 激活的高活性抑制剂。
More
