FAAH (Fatty acid amide hydrolase) is a member of the serine hydrolase family of enzymes. FAAH is an integral membrane hydrolase with a single N-terminal transmembrane domain. In vitro, FAAH has esterase and amidase activity.[8] In vivo, FAAH is the principal catabolic enzyme for a class of bioactive lipids called the fatty acid amides (FAAs). Members of the FAAs include: Anandamide,Other N-acylethanolamines,The sleep-inducing lipid oleamide,The N-acyltaurines.Studies in cells and animals and genetic studies in humans have shown that inhibiting FAAH may be a useful strategy to treat anxiety disorders.
  • ARN 272 EI0484

    ARN 272是FAAH-like anandamide transporter (FLAT) 抑制剂。

  • Arachidonyl serotonin EI0472

    Arachidonyl serotonin是Dual FAAH 抑制剂/TRPV1 拮抗剂。

  • AM 1172 EI0423

    AM 1172是Anandamide uptake inhibitor(摄取抑制剂), 也是FAAH 抑制剂,CB 受体部分激动剂。

  • SA 47 EI2436

    SA 47是选择性 FAAH 抑制剂。

  • PF 3845 EI2127

    PF 3845是选择性 FAAH 抑制剂。

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