HBV
HBV (The hepatitis B virus) is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and the Woolly monkey hepatitis B virus. The virus is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins. These serotypes are based on a common determinant (a) and two mutually exclusive determinant pairs (d/y and w/r).
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Tenofovir能阻断HIV-1和HBV的逆转录酶,对HIV-1和HIV-2的IC50分别为0.5-2.2 uM和1.6-4.9 uM。
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Entecavir monohydrate是核苷类似物,能抑制逆转录,可作用于慢性乙肝。
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Telbivudine 是一种抗病毒药,用于治疗乙型肝炎感染。
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Emtricitabine是HIV核苷逆转录酶抑制剂(NRTI)。
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Adefovir Dipivoxil可阻断HBV逆转录酶。
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