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PPAR


PPARs (peroxisome proliferator-activated receptors) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.

  • MK-886 EY5645

    MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.

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  • Fenofibric acid EY2647

    Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.

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  • Bezafibrate EY2534

    Bezafibrate is the first clinically tested dual and pan-PPAR co-agonism.

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  • Ciprofibrate EY2423

    Ciprofibrate is a peroxisome proliferator-activated receptor agonist.

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  • Rosiglitazone HCl EY2351

    Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.

    More

  • MK-886 EY5645

    MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.

    More

  • Fenofibric acid EY2647

    Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.

    More

  • Bezafibrate EY2534

    Bezafibrate is the first clinically tested dual and pan-PPAR co-agonism.

    More

  • Ciprofibrate EY2423

    Ciprofibrate is a peroxisome proliferator-activated receptor agonist.

    More

  • Rosiglitazone HCl EY2351

    Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.

    More
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