PKC


PKC (Protein kinase C) is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family. PKC enzymes in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca2+). Hence PKC enzymes play important roles in several signal transduction cascades.
The PKC family consists of fifteen isozymes in humans. They are divided into three subfamilies, based on their second messenger requirements: conventional (or classical), novel, and atypical.
  • FR 236924 EI1146

    FR 236924是选择性 PKCε 激动剂。

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  • D-erythro-Sphingosine (synthetic) EI0954

    D-erythro-Sphingosine (synthetic)是Protein kinase C(PKC) 抑制剂。

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  • CID 2858522 EI0793

    CID 2858522是选择性抑制 PKC诱导的 NF-κB 激活。

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  • CGP 53353 EI0754

    CGP 53353是PKCβII选择性抑制剂。

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  • Calphostin C EI0673

    Calphostin C是活性选择性photo-dependent PKC 抑制剂。

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  • FR 236924 EI1146

    FR 236924是选择性 PKCε 激动剂。

    More
  • D-erythro-Sphingosine (synthetic) EI0954

    D-erythro-Sphingosine (synthetic)是Protein kinase C(PKC) 抑制剂。

    More
  • CID 2858522 EI0793

    CID 2858522是选择性抑制 PKC诱导的 NF-κB 激活。

    More
  • CGP 53353 EI0754

    CGP 53353是PKCβII选择性抑制剂。

    More
  • Calphostin C EI0673

    Calphostin C是活性选择性photo-dependent PKC 抑制剂。

    More
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