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GlyT1


Elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders.

  • Bitopertin EY2764

    Bitopertin is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).

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  • ASP 2535 EI0494

    ASP 2535是活性的，选择性 GlyT1 抑制剂。

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  • AMD 3465 hexahydrobromide EI0430

    AMD 3465 hexahydrobromide是活性的，选择性 CXCR4 拮抗剂。

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  • ALX 5407 hydrochloride EI0420

    ALX 5407 hydrochloride是选择性non-transportable GlyT1 抑制剂。

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  • VUF 11222 EI2919

    VUF 11222是高亲和性非肽类 CXCR3 激动剂。

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