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PP2A


PP2A (Protein phosphatase 2) is an enzyme that in humans is encoded by the PPP2CA gene.[2] The PP2A heterotrimeric protein phosphatase, is a ubiquitous and conserved serine/threonine phosphatase with broad substrate specificity and diverse cellular functions. Among the targets of PP2A are proteins of oncogenic signaling cascades, such as Raf, MEK, and AKT.

  • Fostriecin sodium salt EI1138

    Fostriecin sodium salt是活性的 PP2A，PP4 抑制剂。

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  • LB-100 EY0736

    LB-100是蛋白磷酸酶2A（PP2A）小分子抑制剂，在BxPc-3和Panc-1细胞中IC50值分别为0.85uM和3.87uM.

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