CXCR
CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently seven known CXC chemokine receptors in mammals, named CXCR1 through CXCR7.
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AMD 3465 hexahydrobromide是活性的,选择性 CXCR4 拮抗剂。
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VUF 11222是高亲和性非肽类 CXCR3 激动剂。
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VUF 11207 fumarate是活性的 ACKR3 (CXCR7) 激动剂。
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SB 332235是活性的 CXCR2 拮抗剂。
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SB 265610是活性的 CXCR2 拮抗剂。
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