CXCR


CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently seven known CXC chemokine receptors in mammals, named CXCR1 through CXCR7.
  • AMD 3465 hexahydrobromide EI0430

    AMD 3465 hexahydrobromide是活性的,选择性 CXCR4 拮抗剂。

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  • VUF 11207 fumarate EI2918

    VUF 11207 fumarate是活性的 ACKR3 (CXCR7) 激动剂。

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  • VUF 11222 EI2919

    VUF 11222是高亲和性非肽类 CXCR3 激动剂。

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  • SB 332235 EI2480

    SB 332235是活性的 CXCR2 拮抗剂。

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  • SB 265610 EI2474

    SB 265610是活性的 CXCR2 拮抗剂。

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