NNRTIs
NNRTIs (Non-nucleoside reverse-transcriptase inhibitors) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of HIV. RT is one of the most popular targets in the field of antiretroviral drug development.
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Delavirdine mesylate是非核苷逆转录酶抑制剂。
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Rilpivirine (利匹韦林; R278474, TMC 278) 是HIV的非核苷逆转录酶抑制剂。
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Etravirine是非核苷类逆转录酶抑制剂,对野生型HIV-1的EC50为1.4 nM到4.8 nM。
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Nevirapine (奈韦拉平) 是非核苷类逆转录酶抑制剂(NNRTI),可与核苷类似物结合用于抗HIV。
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