DNA/RNA Synthesis
DNA synthesis is the natural or artificial creation of deoxyribonucleic acid (DNA) molecules.
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D-I03 is a selective inhibitor of RAD52 with a Kd value of 25.8 µM.
D-I03 inhibits ssDNA annealing via RAD52 and D-loop formation, with IC50 values of 5 µM and 8 µM, respectively.
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SCR7 pyrazine is an inhibitor of DNA ligase IV that blocks non-homologous end joining (NHEJ) in a ligase IV‑dependent manner. SCR7 pyrazine enhances the efficiency of Cas9‑mediated homology‑directed repair (HDR). SCR7 pyrazine induces apoptosis and exhibits anticancer activity.
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Procarbazine HCl是一种抗肿瘤药。可作用于霍奇金氏淋巴瘤和一些脑癌。
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6-Mercaptopurine Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
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