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AMQUAR 单克隆抗体抑制剂


  • Nivolumab EY8011

    Nivolumab (anti-PD-1)是一种通过基因工程改造的、人类免疫球蛋白(Ig)G4单克隆抗体，靶向具有负向免疫调节功能的人类细胞表面受体程序性死亡-1（PD-1, PCD-1）；也是一种抑制剂，具有免疫检查点抑制活性和抗肿瘤活性；MW：143.597 KD

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  • Tocilizumab EY8010

    Tocilizumab (anti-human IL-6R)是人源单克隆单体，可与interleukin-6 receptor结合发挥抑制作用。MW: 148 KD

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  • MIK665 EY8009

    MIK665 (S-64315) ，源于 S63845，是一种髓系细胞白血病序列1 (MCL1) 抑制剂，对 MCL1 的 IC50 为 1.81 nM

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  • Tocilizumab MA1040

    Tocilizumab is an anti-interleukin-6 receptor (IL-6R) monoclonal antibody, currently approved for the treatment of systemic juvenile idiopathic arthritis (sJIA) and rheumatoid arthritis.

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  • TrastuzuMab MA1041

    Trastuzumab, an anti- ERBB2 (HER2 or HER-2/neu) humanized monoclonal antibody, is used to treat “HER2-positive” tumors.

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