ERKs


ERKs (extracellular signal–regulated kinases ) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric G protein-coupled receptors, transforming agents, and carcinogens, activate the ERK pathway.
  • ERK5-IN-1 EI1097

    ERK5-IN-1是活性选择性 ERK5 抑制剂。

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  • DEL-22379 EY2404

    DEL-22379抑制ERK二聚化, IC50=0.5 μM。

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  • TMCB EI2788

    TMCB是双效的激酶抑制剂, 抑制CK2,ERK8。

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  • TCS ERK 11e EI2737

    TCS ERK 11e是活性的,选择性 ERK2 抑制剂。

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  • XMD8-92 EY1081

    XMD8-92是ERK5/BMK1抑制剂,对BMK1,DCAMKL2,PLK4和TNK1的Kd分别为80,190,600和890 nM。

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  • ERK5-IN-1 EI1097

    ERK5-IN-1是活性选择性 ERK5 抑制剂。

    More
  • DEL-22379 EY2404

    DEL-22379抑制ERK二聚化, IC50=0.5 μM。

    More
  • TMCB EI2788

    TMCB是双效的激酶抑制剂, 抑制CK2,ERK8。

    More
  • TCS ERK 11e EI2737

    TCS ERK 11e是活性的,选择性 ERK2 抑制剂。

    More
  • XMD8-92 EY1081

    XMD8-92是ERK5/BMK1抑制剂,对BMK1,DCAMKL2,PLK4和TNK1的Kd分别为80,190,600和890 nM。

    More
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