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Quisinostat (JNJ-26481585) is a novel second-generation HDACi inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. , in NSCLC cells. In vitro, quisinostat has shown anti-proliferative activity against NSCLC cell lines. quisinostat extremely changed protein acetylation patterns of A549 cells and inhibited epithelial-mesenchymal transition (EMT) process.
More
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Apicidin是活性的HDAC (histone deacetylase) 抑制剂。
More
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UF 010是Class I HDAC 抑制剂。
More
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TCS HDAC6 20b是选择性 HDAC6 抑制剂。
More
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TC-H 106是Class I histone deacetylase(HDAC) 抑制剂。
More
-
Quisinostat (JNJ-26481585) is a novel second-generation HDACi inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. , in NSCLC cells. In vitro, quisinostat has shown anti-proliferative activity against NSCLC cell lines. quisinostat extremely changed protein acetylation patterns of A549 cells and inhibited epithelial-mesenchymal transition (EMT) process.
More
-
Apicidin是活性的HDAC (histone deacetylase) 抑制剂。
More
-
UF 010是Class I HDAC 抑制剂。
More
-
TCS HDAC6 20b是选择性 HDAC6 抑制剂。
More
-
TC-H 106是Class I histone deacetylase(HDAC) 抑制剂。
More
-
Quisinostat (JNJ-26481585) is a novel second-generation HDACi inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. , in NSCLC cells. In vitro, quisinostat has shown anti-proliferative activity against NSCLC cell lines. quisinostat extremely changed protein acetylation patterns of A549 cells and inhibited epithelial-mesenchymal transition (EMT) process.
More
-
Apicidin是活性的HDAC (histone deacetylase) 抑制剂。
More
-
UF 010是Class I HDAC 抑制剂。
More
-
TCS HDAC6 20b是选择性 HDAC6 抑制剂。
More
-
TC-H 106是Class I histone deacetylase(HDAC) 抑制剂。
More
-
Quisinostat (JNJ-26481585) is a novel second-generation HDACi inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. , in NSCLC cells. In vitro, quisinostat has shown anti-proliferative activity against NSCLC cell lines. quisinostat extremely changed protein acetylation patterns of A549 cells and inhibited epithelial-mesenchymal transition (EMT) process.
More
-
Apicidin是活性的HDAC (histone deacetylase) 抑制剂。
More
-
UF 010是Class I HDAC 抑制剂。
More
-
TCS HDAC6 20b是选择性 HDAC6 抑制剂。
More
-
TC-H 106是Class I histone deacetylase(HDAC) 抑制剂。
More
