GPR55
GPR55 is a G protein-coupled receptor that in humans is encoded by the GPR55 gene. GPR55 is coupled to the G-protein G13 and activation of the receptor leads to stimulation of rhoA, cdc42 and rac1. GPR55, along with GPR119 and GPR18, have been implicated as novel cannabinoid receptors.
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CID 16020046是选择性 GPR55 拮抗剂。
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Abn-CBD是选择性 GPR55 激动剂, 神经行为性失活。
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2-Arachidonylglycerol是内源性 cannabinoid 激动剂, 活性的 GPR55 激动剂。
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(-)-Cannabidiol是Natural cannabinoid, GPR55 拮抗剂, 弱效 CB1 拮抗剂, CB2反相激动剂,AMT的抑制剂。
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Palmitoylethanolamide是选择性 GPR55 激动剂。 FAAH,PAA 的底物。
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