Microtubule/Tubulin
Microtubules (micro- + tube + -ule) are a component of the cytoskeleton, found throughout the cytoplasm. They are found in eukaryotic cells, as well as some bacteria, and are formed by the polymerization of a dimer of two globular proteins, alpha and beta tubulin.
Microtubules are very important in a number of cellular processes. They are involved in maintaining the structure of the cell and, together with microfilaments and intermediate filaments, they form the cytoskeleton. They also make up the internal structure of cilia and flagella.They provide platforms for intracellular transport and are involved in a variety of cellular processes, including the movement of secretory vesicles, organelles, and intracellular macromolecular assemblies. They are also involved in chromosome separation, and are the major constituents of mitotic spindles, which are used to pull apart eukaryotic chromosomes.
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Griseofulvin, a production from some strains of the mold Penicillium griseofulvumam, is able to inhibit cell mitosis by interfering with microtubule function.
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D-64131是微管蛋白聚合抑制剂(tubulin)。体内有抗肿瘤活性。。
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Colchicine是微管蛋白(tubulin)抑制剂。
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CMPD-1是非ATP竞争性 p38α 抑制剂， 也是微管蛋白聚合的抑制剂。
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Paclitaxel是一种微管聚合物稳定剂，作用于人内皮细胞，IC50为0.1 pM。
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Griseofulvin, a production from some strains of the mold Penicillium griseofulvumam, is able to inhibit cell mitosis by interfering with microtubule function.
More
-
D-64131是微管蛋白聚合抑制剂(tubulin)。体内有抗肿瘤活性。。
More
-
Colchicine是微管蛋白(tubulin)抑制剂。
More
-
CMPD-1是非ATP竞争性 p38α 抑制剂， 也是微管蛋白聚合的抑制剂。
More
-
Paclitaxel是一种微管聚合物稳定剂，作用于人内皮细胞，IC50为0.1 pM。
More
