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Thrombin


Thrombin is a serine protease that in humans. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.
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    Bivalirudin Trifluoroacetate is a synthetic 20 residue peptide which reversibly inhibits thrombin.

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  • Eltrombopag EY2635

    Eltrombopag, a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).

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  • Triflusal EY2469

    Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.

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  • Dabigatran EY1442

    Dabigatran是可逆的高活性直接凝血酶抑制剂(DTI),Ki为4.5 nM。

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  • Heparin sodium EY1146

    肝素钠盐是一高度硫酸化糖胺聚糖,广泛使用的一种可注射抗凝血剂。

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