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FXR


  • Lithocholic acid EY2471

    Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.

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  • Chenodeoxycholic Acid EY2311

    Chenodeoxycholic acid is a naturally occurring human bile acid.

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  • GW4064 EY0957

    GW4064是一种farnesoid X receptor(FXR)（法尼酯X受体）激动剂，EC50为65 nM。

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  • Obeticholic Acid EY0945

    INT-747是FXR高效选择性激动剂，EC50值为99 nM。

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  • Turofexorate Isopropyl EY0308

    XL335是一种有效的，选择性的FXR激动剂，EC50为4 nM，高选择性作用于其他核受体，如LXR， PPAR， ER等。

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