P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
  • Clomifene citrate EY2855

    Clomifene citrate (Serophene) is a selective estrogen receptor modulator.

    More
  • Gabapentin HCl EY2776

    Gabapentin is a pharmaceutical drug. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.

    More
  • Etonogestrel EY2746

    Etonogestrel is a biologically active metabolite of Desogestrel. The compound is a steroidal progestin.

    More
  • Hydroxyprogesterone caproate EY2747

    Hydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid.

    More
  • Tiagabine EY2748

    Tiagabine is an anti-convulsive medication and a selective gamma-aminobutyric acid (GABA) reuptake inhibitor.

    More
  • Clomifene citrate EY2855

    Clomifene citrate (Serophene) is a selective estrogen receptor modulator.

    More
  • Gabapentin HCl EY2776

    Gabapentin is a pharmaceutical drug. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.

    More
  • Etonogestrel EY2746

    Etonogestrel is a biologically active metabolite of Desogestrel. The compound is a steroidal progestin.

    More
  • Hydroxyprogesterone caproate EY2747

    Hydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid.

    More
  • Tiagabine EY2748

    Tiagabine is an anti-convulsive medication and a selective gamma-aminobutyric acid (GABA) reuptake inhibitor.

    More
  • Current page1, Total Pages31, Total Record151 First Prev 12345 Next Last Goto