Chloride channel

Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many different ions, but are named for chloride because its concentration in vivo is much higher than other anions. Several families of voltage-gated channels and ligand-gated channels have been characterized in humans. Voltage-gated chloride channels display a variety of important physiological and cellular roles that include regulation of pH, volume homeostasis, organic solute transport, cell migration, cell proliferation and differentiation.
  • Torsemide EY2282

    Torsemide is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.

  • GlyH 101 EI1202

    GlyH 101是可逆的 voltage-dependent CFTR 氯离子通道阻断剂。

  • Eact EI1048

    Eact是Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A)的激动剂。

  • DCEBIO EI0940

    DCEBIO是DCEBIO activates Cl-conductance,hKCa3.1 channels。

  • PPQ 102 EI2221

    PPQ 102是活性voltage-independent CFTR 氯离子抑制剂。

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