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Canakinumab, a high-affinity human monoclonal anti IL-1β antibody, neutralizing IL-1β-mediated pathways, is approved for treatment of systemic juvenile idiopathic arthritis (SJIA).
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Certolizumab pegol is a TNF-α antagonist that lacks the Fc portion of the IgG antibody, widely used for the treatment of the inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.
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Cetuximab, an anti-EGFR monoclonal antibody, is used for the treatment of unresectable advanced or recurrent head and neck or colorectal cancer.
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Daclizumab (daclizumab high-yield process) is a humanized monoclonal antibody that binds to the α-subunit (CD25) of the interleukin-2 receptor and favorably modulates the immune environment in multiple sclerosis (MS).
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Denosumab, a human monoclonal antibody against receptor activator of nuclear factor κ B ligand (RANKL), has become widely used as an anti-osteoclastic agent for osteoporosis.
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