参考文献
[1] Tinker et al (2003) 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo. J.Med.Chem. 46 913. PMID: 12620067.
[2] LaBuda et al (2006) Antinociceptive activity of the selective iNOS inhibitor AR-C102222 in rodent models of inflammatory, neuropathic and postoperative pain. Eur.J.Pain 10 505. PMID: 16125426.
[3] Bonnefous et al (2009) Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, Part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models. J.Med.Chem. 52 3047. PMID: 19374401.
分子式
C19H16F2N6O.HCl |
分子量
418.83 |
CAS号
253771-21-0 |
储存方式
﹣20 ℃长期储存。冰袋运输 |
溶剂（常温）
|
DMSO
100 mM |
Water
25 mM |
Ethanol
|
体内溶解度
