参考文献
[1] Hagan et al (1997) Stimulation of 5-HT1B receptors causes hypothermia in the guinea-pig. Eur.J.Pharmacol. 331 169. PMID: 9274976.
[2] Selkirk et al (1998) SB-224289 - a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity. Br.J.Pharmacol. 125 202. PMID: 9776361.
[3] Roberts et al (1998) Differential effects of 5-HT1B/1D receptor antagonists in dorsal and median raphe innervated brain regions. Eur.J.Pharmacol. 346 175. PMID: 9652357.
[4] Gaster et al (1998) The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo. J.Med.Chem. 41 1218. PMID: 9548813.
分子式
C32H32N4O3.HCl |
分子量
557.09 |
CAS号
180084-26-8 |
储存方式
﹣20 ℃长期储存。冰袋运输 |
溶剂（常温）
|
DMSO
10 mM |
Water
|
Ethanol
|
体内溶解度
