Caspofungin Acetate 是抗真菌剂。
Caspofungin acetate is a lipopeptide antifungal drug.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] McGee WT, et al. Crit Care Med, 2003, 31(5), 1577-1578.
分子式 C56H96N10O19 |
分子量 1213.42 |
CAS号 179463-17-3 |
储存方式 ﹣20 ℃冷藏长期储存。冰袋运输 |
溶剂(常温) |
DMSO 80 mM |
Water 80 mM |
Ethanol <1 mg/mL |
体内溶解度
NCT Number | Conditions | Interventions | Sponsor/Collaborators | Phases | Start Date | Last Updated |
NCT00292071 | Fungal Infection | Drug: caspofungin acetate | Merck Sharp & Dohme Corp. | Phase 2 | 2004-05-01 | 2017-02-20 |
NCT00635648 | Fungal Infection | Drug: caspofungin acetate | Merck Sharp & Dohme Corp. | Phase 3 | 2008-01-01 | 2017-02-21 |
NCT01533558 | Invasive Fungal Infection | Drug: caspofungin | Radboud University | 2012-01-01 | 2013-08-28 | |
NCT00404092 | Invasive Aspergillosis | Drug: caspofungin | University of Cologne | Phase 2 | 2006-10-01 | 2013-07-25 |
NCT02596984 | Shock | Drug: Caspofungin | Centre Hospitalier Universitaire de Saint Etienne|Merck Sharp & Dohme Corp. | 2015-03-01 | 2016-11-09 | |
NCT00748345 | Thermal Injury | Drug: Caspofungin (drug) | Assistance Publique - Hôpitaux de Paris | Phase 2|Phase 3 | 2009-02-01 | 2011-12-15 |
NCT01968395 | Bacterial Infections and Mycoses|Liver Disease | Drug: Caspofungin 70 mg | Erasme University Hospital | Phase 4 | 2013-09-01 | 2013-10-23 |
NCT01318148 | Fungal Infection | Drug: caspofungin | Werner J. Heinz|Merck Sharp & Dohme Corp.|Wuerzburg University Hospital | Phase 2 | 2011-04-01 | 2014-01-08 |
NCT00330395 | Candidiasis | Drug: caspofungin acetate | Merck Sharp & Dohme Corp. | Phase 2 | 2006-05-01 | 2017-02-20 |
NCT01062165 | Obesity|Fungal Infection | Drug: Caspofungin | Texas Tech University Health Sciences Center|National Center for Research Resources (NCRR)|University of Texas Southwestern Medical Center | Phase 4 | 2010-02-01 | 2016-12-21 |
NCT01499433 | Invasive Pulmonary Aspergillosis|Chronic Obstructive Pulmonary Disease | Drug: caspofungin | The First Affiliated Hospital of Guangzhou Medical University|Merck Sharp & Dohme Corp. | Phase 4 | 2012-01-01 | 2014-01-22 |
NCT01045798 | Invasive Candidiasis | Drug: Caspofungin acetate|Drug: Placebo | Merck Sharp & Dohme Corp.|Mycoses Study Group | Phase 2 | 2010-12-01 | 2017-02-21 |
NCT00238355 | Infection|Unspecified Adult Solid Tumor, Protocol Specific | Drug: caspofungin acetate|Drug: voriconazole | OHSU Knight Cancer Institute|National Cancer Institute (NCI) | Phase 2 | 2003-08-01 | 2011-12-12 |
NCT00388167 | Candidiasis|Aspergillosis | Drug: Caspofungin | PETHEMA Foundation|GTEI|SEMICYUC | Phase 4 | 2004-03-01 | 2009-05-11 |
NCT02510053 | Invasive Fungal Infection | Drug: Caspofungin | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2014-07-01 | 2015-07-26 | |
NCT01994096 | Critically Ill|Suspected Invasive Candidiasis | Drug: Caspofungin | University Medical Center Groningen | Phase 4 | 2013-11-01 | 2015-10-29 |
NCT00082537 | Neutropenia|Fever | Drug: caspofungin acetate|Drug: Comparator: AmBisome | Merck Sharp & Dohme Corp. | Phase 2 | 2004-04-01 | 2017-02-20 |
NCT01503515 | Fungal Infection|Hematopoietic/Lymphoid Cancer | Drug: caspofungin acetate|Drug: fluconazole|Drug: voriconazole|Other: laboratory biomarker analysis | Children's Oncology Group|National Cancer Institute (NCI) | Phase 3 | 2013-03-01 | 2017-01-18 |
NCT00095316 | Candidiasis | Drug: Caspofungin|Other: Placebo | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 3 | 2004-10-01 | 2014-12-04 |
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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