Home > Antifungal & > Caspofungin Acetate

Caspofungin Acetate

醋酸卡泊芬净,MK-0991,Cancidas,L 743872,L 743873,MK 0991

Caspofungin Acetate 是抗真菌剂。

目录号
EY1821
EY1821
EY1821
EY1821
纯度
99.35%
99.35%
99.35%
99.35%
规格
5 mg
10 mg
25 mg
50 mg
原价
480.00_
865.00_
1,698.00_
2,650.00_
售价
480.00_
865.00_
1,698.00_
2,650.00_
库存
现货
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Caspofungin acetate is a lipopeptide antifungal drug.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] McGee WT, et al. Crit Care Med, 2003, 31(5), 1577-1578.

    分子式
    C56H96N10O19
    分子量
    1213.42
    CAS号
    179463-17-3
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    80 mM
    Water
    80 mM
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT00292071 Fungal Infection Drug: caspofungin acetate Merck Sharp & Dohme Corp. Phase 2 2004-05-01 2017-02-20
    NCT00635648 Fungal Infection Drug: caspofungin acetate Merck Sharp & Dohme Corp. Phase 3 2008-01-01 2017-02-21
    NCT01533558 Invasive Fungal Infection Drug: caspofungin Radboud University 2012-01-01 2013-08-28
    NCT00404092 Invasive Aspergillosis Drug: caspofungin University of Cologne Phase 2 2006-10-01 2013-07-25
    NCT02596984 Shock Drug: Caspofungin Centre Hospitalier Universitaire de Saint Etienne|Merck Sharp & Dohme Corp. 2015-03-01 2016-11-09
    NCT00748345 Thermal Injury Drug: Caspofungin (drug) Assistance Publique - Hôpitaux de Paris Phase 2|Phase 3 2009-02-01 2011-12-15
    NCT01968395 Bacterial Infections and Mycoses|Liver Disease Drug: Caspofungin 70 mg Erasme University Hospital Phase 4 2013-09-01 2013-10-23
    NCT01318148 Fungal Infection Drug: caspofungin Werner J. Heinz|Merck Sharp & Dohme Corp.|Wuerzburg University Hospital Phase 2 2011-04-01 2014-01-08
    NCT00330395 Candidiasis Drug: caspofungin acetate Merck Sharp & Dohme Corp. Phase 2 2006-05-01 2017-02-20
    NCT01062165 Obesity|Fungal Infection Drug: Caspofungin Texas Tech University Health Sciences Center|National Center for Research Resources (NCRR)|University of Texas Southwestern Medical Center Phase 4 2010-02-01 2016-12-21
    NCT01499433 Invasive Pulmonary Aspergillosis|Chronic Obstructive Pulmonary Disease Drug: caspofungin The First Affiliated Hospital of Guangzhou Medical University|Merck Sharp & Dohme Corp. Phase 4 2012-01-01 2014-01-22
    NCT01045798 Invasive Candidiasis Drug: Caspofungin acetate|Drug: Placebo Merck Sharp & Dohme Corp.|Mycoses Study Group Phase 2 2010-12-01 2017-02-21
    NCT00238355 Infection|Unspecified Adult Solid Tumor, Protocol Specific Drug: caspofungin acetate|Drug: voriconazole OHSU Knight Cancer Institute|National Cancer Institute (NCI) Phase 2 2003-08-01 2011-12-12
    NCT00388167 Candidiasis|Aspergillosis Drug: Caspofungin PETHEMA Foundation|GTEI|SEMICYUC Phase 4 2004-03-01 2009-05-11
    NCT02510053 Invasive Fungal Infection Drug: Caspofungin Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 2014-07-01 2015-07-26
    NCT01994096 Critically Ill|Suspected Invasive Candidiasis Drug: Caspofungin University Medical Center Groningen Phase 4 2013-11-01 2015-10-29
    NCT00082537 Neutropenia|Fever Drug: caspofungin acetate|Drug: Comparator: AmBisome Merck Sharp & Dohme Corp. Phase 2 2004-04-01 2017-02-20
    NCT01503515 Fungal Infection|Hematopoietic/Lymphoid Cancer Drug: caspofungin acetate|Drug: fluconazole|Drug: voriconazole|Other: laboratory biomarker analysis Children's Oncology Group|National Cancer Institute (NCI) Phase 3 2013-03-01 2017-01-18
    NCT00095316 Candidiasis Drug: Caspofungin|Other: Placebo National Institute of Allergy and Infectious Diseases (NIAID) Phase 3 2004-10-01 2014-12-04

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 :
  • 收件地址 :
  • 电话号码 :
  • 单位名称 :
  • 产品货号 :
  • 产品规格 :
  • 发票抬头以及单位税号 :