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Ciprofloxacin

环丙沙星,环丙氟哌酸,Bay-o-9867,Ciprobay,Cipro,Cipro IV

Ciprofloxacin是氟喹诺酮类广谱抗生素。

目录号
EY1678
EY1678
EY1678
纯度
99.55%
99.55%
99.55%
规格
500 mg
1 g
5 g
原价
345
365
785
售价
345
365
785
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Ciprofloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity, with MIC90 of 0.024-6 μM.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Wise R, et al. Antimicrob Agents Chemother, 1983, 23(4), 559-564.
    [2] Hoffken, G., et al.: Antimicrob. Ag. Chemother., 27, 375 (1985)
    [3] Scully, B.E., et al.: Lancet, 1, 819 (1986)

    分子式
    C17H18FN3O3
    分子量
    331.34
    CAS号
    85721-33-1
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    <1 mg/mL
    Water
    Insoluble
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02724046 Meningitis, Meningococcal Drug: Ciprofloxacin Epicentre|Medecins Sans Frontieres, Netherlands Phase 4 2017-01-01 2016-09-21
    NCT00992329 Healthy Drug: ciprofloxacin University of Maryland|Food and Drug Administration (FDA) Phase 1 2013-01-01 2013-11-21
    NCT02967341 Childhood Cancer|Neutropenia Other: Ciprofloxacin administration Universitair Ziekenhuis Brussel Phase 4 2016-03-01 2016-11-15
    NCT02773732 Leukemia|Acute Myelogenous Leukemia|Acute Myeloid Leukemia Drug: Ciprofloxacin|Drug: Etoposide University of Florida Phase 1|Phase 2 2016-09-01 2016-09-22
    NCT02961751 Gonorrhoea Drug: Ciprofloxacin National Institute of Allergy and Infectious Diseases (NIAID) 2016-09-13 2017-03-02
    NCT01789203 BK Virus Infection Drug: Ciprofloxacin|Drug: placebo The Methodist Hospital System Phase 4 2013-01-01 2016-03-15
    NCT00609973 Crohn's Disease Drug: Ciprofloxacin|Drug: Placebo University of North Carolina, Chapel Hill|Crohn's and Colitis Foundation|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Phase 2 2008-05-01 2013-03-21
    NCT01402947 Healthy Drug: Ciprofloxacin XR + MMX Placebo|Drug: MMX Mesalazine/mesalamine + Ciprofloxacin XR Shire Phase 1 2011-07-01 2012-06-01
    NCT01157819 Otitis Externa|Otorhinolaryngologic Diseases|Ear Diseases|Otitis Drug: 0.3% Ciprofloxacin Ear Drops|Drug: FoamOtic Cipro Otic Pharma Phase 2 2010-07-01 2011-03-14
    NCT00910351 Pseudomonas Infection Drug: Ciprofloxacin (Cipro, BAYQ3939) Bayer Phase 1 2009-07-01 2013-11-20
    NCT02661438 Bronchiectasis|Pulmonary Disease, Chronic Obstructive Drug: Placebo to Ciprofloxacin DPI (BAYQ3939) Bayer|Novartis 2016-01-01 2016-04-06
    NCT00668044 Burns|Bacterial Infections Drug: Ciprofloxacin (BAYO9867)|Drug: Ciprofloxacin (BAYO9867) Bayer Phase 3 2002-11-01 2009-10-26
    NCT02326103 Alcoholic Hepatitis|Alcoholic Cirrhosis Drug: Ciprofloxacin|Drug: Placebo Helsinki University Early Phase 1 2015-04-01 2017-01-18
    NCT00431028 Inflammation|Bacterial Infections Device: slow delivery ciprofloxacin + triamcinolone Federal University of S茫o Paulo Phase 1|Phase 2 2005-09-01 2008-03-06
    NCT01753115 Anthrax Biological: BioThrax|Drug: Ciprofloxacin Emergent BioSolutions|Department of Health and Human Services Phase 2 2012-12-01 2014-11-18
    NCT02598362 Urinary Tract Infection|Pyelonephritis Drug: ciprofloxacin University Hospital, Ghent|Universitair Ziekenhuis Brussel Phase 4 2015-04-01 2015-11-04
    NCT00481689 Urinary Tract Infections Drug: Cipro XR (Ciprofloxacin, BAYQ3939) Bayer Phase 4 2004-05-01 2009-06-25
    NCT00785980 Healthy Drug: Quinine Sulfate Capsules 324 mg|Drug: Ciprofloxacin 500 mg|Drug: Quinine Sulfate Capsules 324 mg Mutual Pharmaceutical Company, Inc. Phase 1 2008-09-01 2012-07-31
    NCT00930982 Bronchiectasis Drug: Ciprofloxacin (Cipro, BAYQ3939)|Drug: Placebo Bayer|Novartis Phase 2 2009-06-01 2014-11-28
    NCT01319435 Pharmacokinetics of Ciprofloxacin in Neonates Procedure: Collection of biological samples Liverpool Women's NHS Foundation Trust|University of Liverpool Phase 1 2011-01-01 2015-10-09
    NCT01542801 Adverse Reaction to Other Drugs and Medicines Drug: Norfloxacin|Drug: ciprofloxacin Korea University|Sungkyunkwan University|Kyungpook National University|Soon Chun Hyang University Phase 4 2011-08-01 2016-12-27
    NCT00194532 Urinary Tract Infection Drug: Cefpodoxime|Drug: Ciprofloxacin University of Washington 2005-06-01 2014-06-03
    NCT00741052 Cholera Drug: Ciprofloxacin|Drug: Azithromycin International Centre for Diarrhoeal Disease Research, Bangladesh Phase 3 2007-07-01 2011-07-11
    NCT01243437 Plague Drug: ciprofloxacin|Drug: doxyxcycline Centers for Disease Control and Prevention|MRC/UVRI Uganda Research Unit on Aids|Ministry of Health, Uganda Phase 2 2010-12-01 2012-09-10

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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