Home > AChE & > Acetylcysteine

Acetylcysteine

N-乙酰-半胱氨酸,LNAC,NAC,Acetadote

Acetylcysteine是营养补充剂。

目录号
EY1613
EY1613
EY1613
纯度
99.36%
99.36%
99.36%
规格
500 mg
1 g
5 g
原价
200
300
480
售价
200
300
480
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Acetylcysteine is a derivative of cysteine; an acetyl group that is attached to the nitrogen atom. This compound is sold as a dietary supplement commonly claiming antioxidant and liver protecting effects.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Alvirez-Freites EJ, et al. Antimicrob Agents Chemother, 2002, 46(4), 1022-1025.
    [2] Tsai, J.C., et al. 1996. J. Biol. Chem. 271: 3667-3670.
    [3] Tirouvanziam, R., et al. 2006. Proc. Natl. Acad. Sci. U.S.A. 103: 4628-4633.
    [4] Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161: 1907-1911.

    分子式
    C5H9NO3S
    分子量
    163.19
    CAS号
    616-91-1
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    >30 mg/mL
    Water
    >30 mg/mL
    Ethanol
    >20 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02124525 Tobacco Smoking|Oxidative Stress|Inflammation Drug: N-acetylcysteine Universidade Estadual de Londrina Phase 3 2013-02-01 2014-04-24
    NCT02865629 Depression Drug: N-acetyl cysteine University of Cincinnati 2016-08-01 2017-03-21
    NCT01808521 Purpura, Thrombotic Thrombocytopenic|TTP Drug: N-Acetylcysteine Bloodworks (Puget Sound Blood Center)|University of Washington Early Phase 1 2013-05-01 2016-10-14
    NCT01403506 Disorder Related to Renal Transplantation Drug: N-acetyl Cysteine Shahid Beheshti University of Medical Sciences Phase 3 2011-04-01 2011-07-26
    NCT00967005 Gambling|Tobacco Use Disorder Drug: N Acetyl Cysteine|Other: Sugar Pill Yale University|National Institute on Drug Abuse (NIDA)|University of Minnesota - Clinical and Translational Science Institute Phase 2 2009-09-01 2014-03-10
    NCT00998972 Brain Death|Chronic Renal Insufficiency Drug: N-acetylcysteine Institut d'Anesthesiologie des Alpes Maritimes Phase 3 2006-09-01 2011-07-09
    NCT00532688 Heart Failure, Congestive|Kidney Failure, Chronic Drug: N-acetylcysteine Bayside Health|The Alfred Phase 2|Phase 3 2007-09-01 2007-09-19
    NCT02505477 Schizophrenia|Cognitive Deficits|Schizophrenia; Negative Type Drug: N-acetylcysteine|Other: Treatment as Usual University of California, Los Angeles Phase 4 2017-02-06 2017-02-08
    NCT01866644 Unspecified Complication of Liver Transplant Drug: N-acetylcysteine|Drug: Saline Instituto de Investigacion Sanitaria La Fe Phase 3 2011-09-01 2015-07-21
    NCT00896025 Acute Liver Failure|Fulminant Hepatic Failure Drug: N-acetylcysteine William Lee|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|University of Texas Southwestern Medical Center Phase 4 2008-12-01 2014-01-29
    NCT00637624 Carcinoma, Non-Small-Cell Lung|Carcinoma, Small Cell Lung|Mesothelioma Drug: N-Acetylcysteine|Drug: Placebo Rijnstate Hospital 2008-03-01 2011-08-08
    NCT02212678 Parkinson Disease Drug: N-acetylcysteine capsule University of Minnesota - Clinical and Translational Science Institute|Parkinson's Disease Society of the United Kingdom Phase 2 2014-09-01 2016-02-17
    NCT00568087 Alcoholism Drug: N-acetylcysteine|Drug: Placebo Minneapolis Veterans Affairs Medical Center|Minnesota Veterans Medical Research and Education Foundation Phase 1|Phase 2 2007-12-01 2013-08-28
    NCT00248625 Acute Liver Failure|Hepatic Encephalopathy Drug: N-acetylcysteine|Drug: Placebo University of Pittsburgh|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Phase 3 2000-01-01 2016-06-16
    NCT01118663 Acetaminophen Overdose Drug: Acetadote EF (Ethylenediaminetetraacetic Acid (EDTA) - Free)|Drug: Acetadote Cumberland Pharmaceuticals Phase 3 2010-09-01 2014-08-01
    NCT01726465 Ischemic Reperfusion Injury|Insufficiency; Hepatic, Postoperative|Liver Tumour Drug: Methylprednisolone|Drug: N-acetylcysteine Istituto Clinico Humanitas Phase 2 2012-11-01 2013-11-09
    NCT02788292 Adipose Tissue Atrophy|Deformity of Reconstructed Breast|Graft Loss Drug: Acetylcysteine Michael Bezuhly|Nova Scotia Health Authority Phase 4 2016-07-01 2016-05-27

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 :
  • 收件地址 :
  • 电话号码 :
  • 单位名称 :
  • 产品货号 :
  • 产品规格 :
  • 发票抬头以及单位税号 :