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DAPI

目录号
EY2828
EY2828
EY2828
EY2828
纯度
98.63%
98.63%
98.63%
98.63%
规格
1 mg
5 mg
10 mg
25 mg
原价
230
500
650
1290
售价
230
500
650
1290
库存
现货
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    DAPI is a fluorescent DNA stain. It binds to AT-rich regions of DNA. Cell permeable at high concentrations.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Russell et al (1975) A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature 253 461.
    [2] Mildner et al (1978) Interaction of 4'-6-diamidino-2-phenylindole to nucleic acids, and its implication to their template activity in RNA-polymerase reaction of E. coli bacteria and of Friend-virus infected mouse spleen. Cancer Lett. 4 89.

    分子式
    C16H15N5.2HCl
    分子量
    350.25
    CAS号
    28718-90-3
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    10 mg/mL
    Water
    10 mg/mL
    Ethanol
    10 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT02456571 Prostate Cancer Device: CTC biomarker expression prevalence Duke University|Janssen Research & Development, LLC 2016-11-01 2017-01-03
    NCT02198092 Familial Adenomatous Polyposis|Map Syndrome|Lynch Syndrome|Hnpcc|Colorectal Cancer Other: Epi proColon Testing University of Pennsylvania|Epigenomics, Inc 2014-07-01 2016-09-06
    NCT02500693 Lung Neoplasms|Pulmonary Disease, Chronic Obstructive Biological: Isolation of circulating tumor cells (CTC) from veinous blood Centre Hospitalier Universitaire de Nice 2015-11-01 2016-07-08
    NCT01987726 Recurrent Breast Cancer|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Breast Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer Other: cytology specimen collection procedure|Other: laboratory biomarker analysis Ohio State University Comprehensive Cancer Center|Foundation Medicine 2013-09-01 2017-01-28
    NCT02654925 Obesity Procedure: Adipose Tissue Biopsy University of Colorado, Denver 2016-03-01 2016-08-23
    NCT02306512 Lentigo Maligna|Melanoma In Situ Procedure: H&E|Procedure: IHC MART-1|Procedure: IF MART-1|Procedure: IF cocktail University of Miami|University of Miami Sylvester Comprehensive Cancer Center 2015-06-01 2015-12-02
    NCT02482740 Uterine Cervical Neoplasms Drug: Letrozole|Drug: tamoxifen Buddhist Tzu Chi General Hospital|Chang Gung Memorial Hospital|Chung Shan Medical University|China Medical University Hospital|National Cheng-Kung University Hospital|Kaohsiung Medical University Chung-Ho Memorial Hospital|Kaohsiung Veterans General Hospital.|Taiwan Ministry of Science and Technology Phase 2 2015-05-01 2015-06-23

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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