DAPI is a fluorescent DNA stain. It binds to AT-rich regions of DNA. Cell permeable at high concentrations.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Russell et al (1975) A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature 253 461.
[2] Mildner et al (1978) Interaction of 4'-6-diamidino-2-phenylindole to nucleic acids, and its implication to their template activity in RNA-polymerase reaction of E. coli bacteria and of Friend-virus infected mouse spleen. Cancer Lett. 4 89.
分子式 C16H15N5.2HCl |
分子量 350.25 |
CAS号 28718-90-3 |
储存方式 ﹣20 ℃冷藏长期储存。冰袋运输 |
溶剂(常温) |
DMSO 10 mg/mL |
Water 10 mg/mL |
Ethanol 10 mg/mL |
体内溶解度
NCT Number | Conditions | Interventions | Sponsor/Collaborators | Phases | Start Date | Last Updated |
NCT02456571 | Prostate Cancer | Device: CTC biomarker expression prevalence | Duke University|Janssen Research & Development, LLC | 2016-11-01 | 2017-01-03 | |
NCT02198092 | Familial Adenomatous Polyposis|Map Syndrome|Lynch Syndrome|Hnpcc|Colorectal Cancer | Other: Epi proColon Testing | University of Pennsylvania|Epigenomics, Inc | 2014-07-01 | 2016-09-06 | |
NCT02500693 | Lung Neoplasms|Pulmonary Disease, Chronic Obstructive | Biological: Isolation of circulating tumor cells (CTC) from veinous blood | Centre Hospitalier Universitaire de Nice | 2015-11-01 | 2016-07-08 | |
NCT01987726 | Recurrent Breast Cancer|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Breast Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer | Other: cytology specimen collection procedure|Other: laboratory biomarker analysis | Ohio State University Comprehensive Cancer Center|Foundation Medicine | 2013-09-01 | 2017-01-28 | |
NCT02654925 | Obesity | Procedure: Adipose Tissue Biopsy | University of Colorado, Denver | 2016-03-01 | 2016-08-23 | |
NCT02306512 | Lentigo Maligna|Melanoma In Situ | Procedure: H&E|Procedure: IHC MART-1|Procedure: IF MART-1|Procedure: IF cocktail | University of Miami|University of Miami Sylvester Comprehensive Cancer Center | 2015-06-01 | 2015-12-02 | |
NCT02482740 | Uterine Cervical Neoplasms | Drug: Letrozole|Drug: tamoxifen | Buddhist Tzu Chi General Hospital|Chang Gung Memorial Hospital|Chung Shan Medical University|China Medical University Hospital|National Cheng-Kung University Hospital|Kaohsiung Medical University Chung-Ho Memorial Hospital|Kaohsiung Veterans General Hospital.|Taiwan Ministry of Science and Technology | Phase 2 | 2015-05-01 | 2015-06-23 |
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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