Epinephrine Bitartrate

酒石酸肾上腺素,Adrenalinium,(-)-Epinephrine (+)-bitartrate salt,L-Adrenaline (+)-bitartrate salt

L-Epinephrine Bitartrate是α和β肾上腺素受体刺激剂,是一种激素和神经递质。

目录号
EY1770
EY1770
纯度
99.14%
99.14%
规格
1 g
5 g
原价
680
1160
售价
680
1160
库存
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Epinephrine Bitartrate is an alpha- and beta-adrenergic receptor stimulator.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Fabiano B Carvalho et. Al. The Journal of Nutritional Biochemistry, 26(4), 378-390 (2015).
    [2] Yangjie Wei et. Al. AAPS PharmSciTech, 16(2), 455-465 (2015).

    分子式
    C13H19NO9
    分子量
    333.29
    CAS号
    51-42-3
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    66 mg/mL
    Water
    66 mg/mL
    Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01432522 Anaphylaxis Drug: Epinephrine Siriraj Hospital|Mahidol University 2010-07-01 2011-09-12
    NCT01217138 Anaphylaxis Device: Epinephrine autoinjector Gazi University Phase 4 2009-06-01 2010-10-07
    NCT01887405 Handling of Auto-injectors Drug: Adrenaline auto-injector ALK Nordic A/S, Danmark Filial Phase 4 2012-01-01 2013-06-24
    NCT03036202 Cardiac Arrest Drug: Epinephrine Haukeland University Hospital 2017-02-10 2017-02-06
    NCT00997594 Adrenal Tumors Procedure: Radiofrequency ablation Mie University Phase 2|Phase 3 2009-10-01 2015-04-06
    NCT00548886 Congenital Disorders Drug: Epinephrine Emory University|Children's Healthcare of Atlanta 2008-02-01 2015-02-20
    NCT01209507 Adrenal Suppression Other: Chemotherapy University of Colorado, Denver 2010-02-01 2017-03-23
    NCT00768365 Adrenal Cortex Neoplasms Istanbul University 2007-10-01 2008-10-07
    NCT01188577 Asthma|Bronchospasm|Wheezing|Shortness of Breath Drug: Epinephrine Inhalation Aerosol, HFA|Drug: Epinephrine Inhalation Aerosol Amphastar Pharmaceuticals, Inc. Phase 1|Phase 2 2010-08-01 2014-10-21
    NCT00975078 Adrenal Gland Hypofunction Procedure: adrenal insufficiency testing|Drug: prednisone University Hospital, Basel, Switzerland Phase 4 2009-05-01 2011-08-08
    NCT01264653 Cataract Drug: adrenalin Wenzhou Medical University 2010-12-01 2012-07-04
    NCT01664507 Croup|Epinephrine Neublizer Treatment Drug: conventional dose epinephrine|Drug: low dose epinephrine Seoul National University Hospital Phase 4 2012-09-01 2012-08-09
    NCT00591643 Adrenal Tumors|Adrenal Malignancies|Abnormal Hormonal Secretions|Electrolytes Abnormalities Procedure: Imaging, Adrenal acans|Radiation: (NP-59) Memorial Sloan Kettering Cancer Center Phase 1 1977-07-01 2015-12-23
    NCT02368379 Prader Willi Syndrome|Adrenal Insufficiency Other: Low dose (1 mcg) ACTH stimulation test|Other: Overnight metyrapone test Nationwide Children's Hospital 2014-03-01 2015-02-16
    NCT00721929 Adrenal Gland Disease Procedure: MRI University of Michigan 2003-10-01 2012-12-04
    NCT02735018 Cardiovascular Response to Epinephrine Drug: Epinephrine 1:100,000|Drug: Epinephrine 1:200,000 Rio de Janeiro State University Phase 4 2014-12-01 2016-04-06
    NCT00575029 Adrenal Insufficiency Drug: megestrol acetate University of Arkansas 2004-04-01 2011-07-27
    NCT02692313 Diabetes Complications Drug: Epinephrine|Other: Saline infusion University of Maryland|Vanderbilt University Early Phase 1 2016-06-01 2017-02-09
    NCT02694926 Adrenal Insufficiency Other: Education Wuerzburg University Hospital|Dr. Michael Droste, Elisenstrae 12, 26122 Oldenburg|Prof. Dr. Marcus Quinkler, Praxis fr Endokrinologie,10627 Berlin|Dr. Gesine Meyer, Universittsklinikum Frankfurt, 60590 Frankfurt am Main|PD Dr. Nicole Reisch, LMU Mnchen, D-80336 Mnchen|Prof. Dr. Holger Willenberg, Zentrum fr Innere Medizin, D-18057 Rostock|Prof. Johannes Klein, Zentrum Endokrine Medizin, 23564 Lbeck|Dr. med. Tina Kienitz, Charit - Universittsmedizin Berlin, 10117 Berlin|MVZ Endokrinologikum Saarbrcken, Europaallee 15, 66113 Saarbrcken 2014-12-01 2016-03-02
    NCT01284829 Adrenal Tumors Other: FDG-PET scan Assistance Publique Hopitaux De Marseille 2011-02-01 2015-09-29
    NCT02543697 Cushing Syndrome Radiation: Adrenal venous sampling Haukeland University Hospital 2015-02-01 2016-09-07
    NCT00628550 Cardiopulmonary Arrest|Cardiac Arrest Drug: Vasopressin|Drug: Epinephrine University of Texas Southwestern Medical Center|Children's Medical Center Dallas Phase 1 2008-04-01 2010-06-24
    NCT02724761 Dysphagia|Dysphonia|Postoperative Pain Drug: Racemic Epinephrine|Drug: Placebo (for racemic epinephrine) Andrew Chung|More Foundation|Banner Health 2016-09-01 2016-03-30
    NCT02369510 Spinal Anesthesia|Cesarean Section Drug: Low-dose epinephrine|Drug: High-dose epinephrine|Drug: No epinephrine Icahn School of Medicine at Mount Sinai Phase 4 2015-02-01 2016-07-21
    NCT02127840 Primary Aldosteronism Drug: Synacthen infusion during adrenal venous sampling Charles University, Czech Republic|University Hospital Hradec Kralove Phase 4 2011-03-01 2014-04-28

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

  • 相关化合物库

  • 使用AMQUAR产品发表文献后请联系我们

相关推荐

X
  • 联系人 :
  • 收件地址 :
  • 电话号码 :
  • 单位名称 :
  • 产品货号 :
  • 产品规格 :
  • 发票抬头以及单位税号 :