Prednisolone

泼尼松龙

Prednisolone是糖皮质素。

目录号
EY1729
EY1729
EY1729
纯度
99.18%
99.18%
99.18%
规格
500 mg
1 g
5 g
原价
390
495
810
售价
390
495
810
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Kolls J, et al. Proc Soc Exp Biol Med, 1994, 205(3), 220-229.

    分子式
    C21H28O5
    分子量
    360.44
    CAS号
    50-24-8
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    72 mg/mL
    Water
    <1 mg/mL
    Ethanol
    10 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT00632554 Eosinophilic Pneumonia|Chronic Disease Drug: prednisolone 0.5 mg/kg/day for three months|Drug: prednisolone 0.5 mg/kg/day for six months Hamamatsu University Phase 4 2008-06-01 2014-09-18
    NCT00198523 Eye Infections|Postoperative Complications Drug: Prednisolone and Tobramycin|Drug: Prednisolone Bausch & Lomb Incorporated Phase 3 2005-07-01 2013-03-13
    NCT00778596 Chronic Hepatitis B Drug: Prednisolone|Drug: Placebo priming Yun-Fan Liaw|Chang Gung Memorial Hospital Phase 4 2009-02-01 2012-05-24
    NCT02299115 Infantile Spasms Drug: Prednisolone|Drug: Vigabatrin The Hospital for Sick Children Phase 3 2016-09-01 2016-04-16
    NCT00971724 Insulin Resistance|Hyperglycemia|Glucose Intolerance Drug: Placebo|Drug: Prednisolone Merck Sharp & Dohme Corp. 2006-05-01 2015-05-21
    NCT01395251 Rheumatoid Arthritis Drug: Prednisolone Rheumazentrum Ruhrgebiet Phase 2|Phase 3 2012-02-01 2015-05-15
    NCT00662298 Asthma Drug: prednisolone Imperial College London|Royal Brompton & Harefield NHS Foundation Trust Phase 4 2011-06-01 2015-03-25
    NCT02935738 Reproductive Sterility Drug: Prednisolone treatment Barz IVF Center for Infertility Treatment and Embryo Research|University of Baghdad 2014-10-01 2016-10-14
    NCT00982072 Minimal Change Disease Drug: tacrolimus|Drug: prednisolone Imperial College Healthcare NHS Trust Phase 4 2009-12-01 2017-03-03
    NCT02344888 Infertility|Polycystic Ovarian Syndrome Drug: Clomiphene citrate and Prednisolone|Drug: Clomiphene citrate Mohamed Sayed Abdelhafez|Mansoura University Phase 4 2015-02-01 2016-11-18
    NCT00380133 Pulmonary Disease, Chronic Obstructive Drug: SB681323|Drug: Prednisolone|Drug: Placebo GlaxoSmithKline Phase 1 2005-06-01 2012-05-31
    NCT01603030 Eye Infection/Inflammation Other Drug: moxifloxacin 0,5% + prednisolone 1%|Drug: moxifloxacin/prednisolone combination Adapt Produtos Oftalmolgicos Ltda. Phase 3 2012-06-01 2012-05-21
    NCT02587117 Oral Lichen Planus Drug: lycopene|Drug: Prednisolone B.P. Koirala Institute of Health Sciences Phase 4 2013-02-01 2016-01-26
    NCT00135122 Headache Drug: prednisolone Sorlandet Hospital HF Phase 3 2003-09-01 2008-09-11
    NCT02252237 Children Receiving Prednisone or Prednisolone or Methylprednisolone Biological: Pharmacokinetic Assistance Publique - Hpitaux de Paris 2014-12-01 2016-12-15
    NCT01011621 Dermatitis, Atopic|Dermatitis, Contact|Dermatitis, Seborrheic|Psoriasis Drug: 0.5% prednisolone acetate cream|Drug: 0.1% betamethasone valerate cream Mantecorp Industria Quimica e Farmaceutica Ltd. Phase 3 2010-02-01 2009-11-10
    NCT00810849 Tuberculous Pericarditis Drug: Prednisolone|Biological: Mycobacterium w immunotherapy University of Cape Town|Population Health Research Institute Phase 3 2008-12-01 2014-09-02
    NCT00345046 Glaucoma|Cataract Drug: Pred Forte|Drug: EconoPred Plus|Drug: Prednisolone Acetate Indiana University School of Medicine|Indiana University Phase 4 2002-09-01 2015-06-02
    NCT02229136 Stomatitis|Oral Mucositis|Neoplasm of the Breast|Malignant Tumor of Breast Drug: Miracle Mouthwash Plus Hydrocortisone|Drug: Prednisolone US Oncology Research|Novartis Pharmaceuticals Phase 2 2014-09-01 2016-09-15
    NCT02949232 Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Psychotic Disorder NOS Drug: Prednisolone|Drug: Placebo Oral Tablet UMC Utrecht Phase 4 2014-07-01 2016-10-31
    NCT01068392 B-cell Lymphomas Drug: Oxaliplatin, Prednisolone Dong-A University Hospital|Samsung Medical Center|Asan Medical Center|Chung-Ang University|Kyungpook National University|Chonnam National University Hospital|Korea Cancer Center Hospital|Korea University Phase 2 2009-10-01 2014-11-02
    NCT01244334 Cataracts|Corneal Edema|Retinal Structural Change, Deposit and Degeneration|Visual Acuity Reduced Transiently Drug: Difluprednate ophthalmic emulsion 0.05%|Drug: Prednisolone acetate 1% Edward J. Holland|Sirion Therapeutics, Inc.|Alcon Research|Parsons Medical Communications|Cincinnati Eye Institute Northern Kentucky Phase 4 2009-03-01 2012-08-06
    NCT02495662 Renal Dialysis|Hemodynamics|Vascular Remodeling|Neointima Drug: PEG-liposomal prednisolone sodium phosphate|Drug: Placebo Leiden University Medical Center|HagaZiekenhuis|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|OLVG|Medical Center Haaglanden|Reinier de Graaf Groep|Spaarne Gasthuis|Alrijne Hospital|Tergooi Ziekenhuis Phase 2 2015-11-01 2017-03-06
    NCT01039103 Acute Exacerbation of Remitting Relapsing Multiple Sclerosis|Clinically Isolated Syndrome Drug: PEG-liposomal prednisolone sodium phosphate|Drug: Methylprednisolone Galapagos NV Phase 2 2009-12-01 2016-10-05
    NCT00257933 Asthma Drug: Prednisolone high dose|Drug: Prednisolone lower dose Children's Hospital of Philadelphia Phase 4 2006-02-01 2010-12-23

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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