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Ibandronate sodium

伊班膦酸钠,BM-21.0955,BM-21.0955,BM-21.0955

Ibandronate Sodium Monohydrate是高活性的含氮二磷酸盐，可用于骨质疏松。

目录号
EY1716
EY1716
纯度
99.18%
99.18%
规格
100 mg
500 mg
原价
480
1420
售价
480
1420
库存
现货
现货
订购
订购
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  • 生物活性

    Ibandronate is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数


    例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

  • 参考文献

    [1] Morgan C, et al. Microvasc Res, 2009, 78(3), 453-458.

    分子式
    C9H24NNaO8P2    		 分子量
    359.23    		 CAS号
    138926-19-9    		 储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂（常温）
    		 DMSO
    <1 mg/mL    		 Water
    72 mg/mL    		 Ethanol
    <1 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01627886 Healthy Drug: Ibandronate sodium Dr. Reddy's Laboratories Limited Phase 1 2008-09-01 2012-06-27
    NCT01381393 Osteoporosis Drug: Ibandronate GlaxoSmithKline 2007-06-01 2012-11-28
    NCT02604836 Postmenopausal Osteoporosis Drug: Ibandronate Hoffmann-La Roche Phase 4 2004-06-01 2016-11-01
    NCT02598440 Postmenopausal Osteoporosis Drug: Alendronate|Drug: Ibandronate Hoffmann-La Roche Phase 4 2004-03-01 2016-11-01
    NCT02598453 Postmenopausal Osteoporosis Drug: Ibandronate Hoffmann-La Roche Phase 4 2005-01-01 2016-11-01
    NCT02114489 Aseptic;|Hip Necrosis Drug: ibandronate|Drug: Placebo Brigitte Jolles, MD|University of Lausanne Hospitals Phase 3 2014-06-01 2016-05-12
    NCT02553707 Pain; Bone Neoplasms; Neoplasm Metastasis Drug: Ibandronate Hoffmann-La Roche Phase 4 2006-07-01 2015-09-16
    NCT02561039 Pain; Bone Neoplasms; Neoplasm Metastasis Drug: Ibandronate Hoffmann-La Roche Phase 3 2006-12-01 2016-11-01
    NCT02564107 Pain; Bone Neoplasms; Neoplasm Metastasis Drug: Ibandronate Hoffmann-La Roche Phase 4 2004-11-01 2016-11-01
    NCT02598934 Post Menopausal Osteoporosis Drug: Ibandronate Hoffmann-La Roche Phase 4 2004-08-01 2016-02-10
    NCT00545779 Post-Menopausal Osteoporosis Drug: Ibandronate Hoffmann-La Roche Phase 3 2006-12-01 2016-09-09
    NCT02716792 Pain; Bone Neoplasms; Neoplasm Metastasis Drug: Ibandronate Hoffmann-La Roche Phase 3 2006-01-01 2016-03-18
    NCT01376102 Osteoporosis Drug: BONVIVA(ibandronate) injection GlaxoSmithKline 2007-11-01 2014-06-12
    NCT00545363 Postmenopausal Osteoporosis Drug: Ibandronate Hoffmann-La Roche Phase 4 2006-04-01 2016-08-31
    NCT00148915 Osteoporosis Drug: ibandronate|Drug: Placebo Hoffmann-La Roche Phase 4 2005-08-01 2016-11-04
    NCT02739594 Multiple Myeloma Drug: Ibandronate|Drug: Zoledronate Hoffmann-La Roche|Roche Pharma AG Phase 3 2006-02-01 2016-06-09
    NCT00327990 Osteoporosis Drug: Ibandronate|Drug: Alendronate GlaxoSmithKline Phase 4 2005-04-01 2017-01-18
    NCT02271204 Osteoporosis Drug: Ibandronic acid Clinic of Endocrinology and Metabolic Disorders, Macedonia|Clinic for Orthopedic Surgery, Skopje|General Hospital, Kumanovo|General Hospital, Struga|Medical Faculty, Institute for Epidemiology and Biostatistics, Skopje 2009-03-01 2014-10-20
    NCT00301886 Breast Cancer|Hypercalcemia of Malignancy|Metastatic Cancer|Pain Drug: ibandronate|Drug: zoledronate|Procedure: quality-of-life assessment Southwest Oncology Group|National Cancer Institute (NCI) Phase 3 2006-05-01 2013-11-11
    NCT00545051 Postmenopausal Osteoporosis Drug: Placebo|Drug: ibandronate Hoffmann-La Roche|GlaxoSmithKline Phase 4 2006-05-01 2016-04-05
    NCT00492843 Lung Cancer Drug: Ibandronate (Bondronat) Chinese Society of Lung Cancer Phase 4 2007-07-01 2016-02-14
    NCT00271713 Osteoporosis, Postmenopausal Drug: ibandronate, calcium and vitamin D|Drug: placebo,calcium and vitamin D Charite University, Berlin, Germany Phase 4 2006-03-01 2009-01-27
    NCT00405392 Postmenopausal Osteoporosis Drug: Ibandronate (SB743830HD) Hoffmann-La Roche Phase 4 2007-03-01 2016-10-03
    NCT00683163 Osteoporosis Drug: PTH(1-84)|Drug: Ibandronate|Other: Placebo injection|Other: Placebo pills University of California, San Francisco Phase 2|Phase 3 2008-05-01 2013-08-29

    注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。

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