Home > Phospholipase & > Halobetasol Propionate

Halobetasol Propionate

卤贝他索丙酸酯,BMY-30056,CGP-14458,Ultravate,Ulobetasol propionate,BMY 30056,BMY30056

Halobetasol propionate是一种皮肤外用使用合成类固醇,具有抗炎,止痒和收缩血管的作用。

目录号
EY1652
EY1652
EY1652
EY1652
EY1652
纯度
99.67%
99.67%
99.67%
99.67%
99.67%
规格
5 mg
10 mg
10 mg
50 mg
100 mg
原价
248
415
735
758
1120
售价
248
415
735
758
1120
库存
现货
现货
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Halobetasol Propionate is an anti-inflammatory and a dermatologic agent commonly used to treat psoriasis.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Mohandas S, et al. Indian J Dermatol Venereol Leprol, 2009, 75(2), 186-187.

    分子式
    C25H31ClF2O5
    分子量
    484.96
    CAS号
    66852-54-8
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    100 mg/mL
    Water
    <1 mg/mL
    Ethanol
    35 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT00715975 Psoriasis Drug: halobetasol|Drug: clobetasol Azidus Brasil Phase 2|Phase 3 2008-07-01 2010-08-31
    NCT00865605 Healthy Drug: Halobetasol Propionate 0.05% Ointment, single exposure|Drug: Ultravate 0.05% ointment, single exposure Actavis Inc. Phase 1 2003-12-01 2010-08-13
    NCT00865267 Healthy Drug: Ultravate 0.05% ointment, single exposure Actavis Inc. Phase 1 2003-12-01 2010-08-13
    NCT00990561 Stable Plaque Psoriasis Drug: Ultravate ointment twice daily + LacHydrin lotion twice daily|Drug: Ultravate ointment once daily + LacHydrin lotion twice daily University of California, San Francisco Phase 4 2009-07-01 2012-12-04
    NCT00802958 Healthy Drug: Halobetasol Propionate 0.05% Ointment-Reference Product|Drug: Halobetasol Propionate 0.05% Ointment-Test Product Perrigo Company 2003-07-01 2012-03-15
    NCT00803166 Healthy Drug: Halobetasol Propionate 0.05% Cream-Reference Product|Drug: Halobetasol Propionate 0.05% Cream-Test product 1|Drug: Halobetasol Propionate 0.05% Cream-Test Product 2 Perrigo Company 2004-01-01 2012-03-15
    NCT01111123 Plaque Psoriasis Drug: Lac-Hydrin lotion (ammonium lactate lotion 12%) ; UItravate ointment (halobetasol propionate ointment 0.05%)|Drug: Lac-Hydrin lotion (ammonium lactate lotion 12%); placebo ointment Icahn School of Medicine at Mount Sinai Phase 4 2009-01-01 2016-05-25
    NCT01610596 Psoriasis|Plaque Psoriasis Drug: Halobetasol Propionate Lotion 0.05%|Drug: Placebo Therapeutics, Inc. Phase 2 2011-11-01 2016-04-11
    NCT02785172 Psoriasis Drug: IDP-118 Vehicle Lotion|Drug: IDP-118 Vehicle Cream|Drug: IDP-118 Lotion|Drug: Ultravate Cream Valeant Pharmaceuticals International, Inc. Phase 2 2016-04-01 2016-08-15
    NCT01166646 Plaque Psoriasis Drug: Halobetasol Proprionate Lotion 0.05%|Drug: Halobetasol Proprionate Cream 0.05% Therapeutics, Inc. Phase 2 2010-07-01 2016-04-11
    NCT02785185 Psoriasis Drug: IDP-122 Vehicle Lotion|Drug: IDP-122 Vehicle Cream|Drug: IDP-122 Lotion|Drug: Ultravate Cream Valeant Pharmaceuticals International, Inc. Phase 2 2016-06-01 2016-08-15
    NCT02462083 Plaque Psoriasis Drug: IDP-118 Lotion Valeant Pharmaceuticals International, Inc.|Dow Pharmaceutical Sciences Phase 3 2015-07-01 2016-08-15
    NCT01404338 Psoriasis Drug: Halobetasol 0.05% ointment|Drug: Placebo Ointment Patel, Rita Vikram, M.D. Phase 1 2011-06-01 2011-07-27
    NCT03065556 Plaque Psoriasis Drug: 188-0551 Solution|Drug: Vehicle Solution Therapeutics, Inc. Phase 2 2017-01-26 2017-02-22
    NCT03058744 Psoriasis Drug: IDP-118 Lotion|Drug: HP Monad Lotion|Drug: Ultravate Cream|Drug: Tazorac Cream Valeant Pharmaceuticals International, Inc. Phase 1 2015-06-01 2017-02-16
    NCT02515097 Plaque Psoriasis Drug: IDP-122 Lotion|Drug: IDP-122 Vehicle Lotion Valeant Pharmaceuticals International, Inc. Phase 3 2015-10-01 2016-05-24
    NCT02514577 Plaque Psoriasis Drug: IDP-122 Lotion|Drug: IDP-122 Vehicle Lotion Valeant Pharmaceuticals International, Inc. Phase 3 2015-10-01 2016-05-24
    NCT02045277 Plaque Psoriasis Drug: IDP-118 Lotion|Drug: IDP-118 Monad HP Lotion|Drug: IDP-118 Monad Taz Lotion|Drug: IDP-118 Vehicle Lotion Valeant Pharmaceuticals International, Inc.|Dow Pharmaceutical Sciences Phase 2 2014-02-01 2016-08-15
    NCT00234728 Psoriasis Device: Occlusive dressing Teikoku Pharma USA 2005-09-01 2008-06-30

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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