Progesterone

孕酮,孕激素,黄体酮,孕甾酮

Progesterone is a critical hormone for the maintenance of pregnancy, menstrual cycle, endometrium and functions with its receptor.

目录号
EY1561
EY1561
EY1561
纯度
99.82%
99.82%
99.82%
规格
10 mg
100 mg
500 mg
原价
120
200
300
售价
120
200
300
库存
现货
现货
现货
订购
订购
订购
订购
订购
订购
  • 生物活性

    Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

  • 体外研究

  • 体内研究

  • 激酶实验

  • 细胞实验

  • 动物实验

  • 不同实验动物依据体表面积的等效剂量转换表(数据来源于FDA指南)

    动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 AKm系数


    例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。


  • 参考文献

    [1] Owen GI, et al. J Biol Chem,1998, 273(17), 10696-10701.

    分子式
    C21H30O2
    分子量
    314.47
    CAS号
    57-83-0
    储存方式
    ﹣20 ℃冷藏长期储存。冰袋运输
    溶剂(常温)
    DMSO
    23 mg/mL
    Water
    <1 mg/mL
    Ethanol
    60 mg/mL

    体内溶解度

  • Clinical Trial Information ( data from http://clinicaltrials.gov )

    NCT Number Conditions Interventions Sponsor/Collaborators Phases Start Date Last Updated
    NCT01940653 Progesterone Supplementation Drug: Progesterone Universitair Ziekenhuis Brussel Phase 4 2012-11-01 2014-05-20
    NCT02304237 Premature Birth Drug: Vaginal progesterone|Drug: Intramuscular progesterone Ewha Womans University Mokdong Hospital|Samsung Medical Center|Han Wha Pharma Co., Ltd.|Ministry of Health & Welfare, Korea Phase 3 2014-12-01 2014-11-26
    NCT01180296 Preterm Birth Drug: oral micronized progesterone|Drug: Identical Placebo tablet Fetal Medicine Foundation Phase 3 2006-11-01 2012-03-02
    NCT02779582 Perimenopause|Menstrual Cramps Drug: Oral Micronized Progesterone|Drug: Placebo University of British Columbia Phase 3 2015-06-01 2016-11-09
    NCT00218257 Cocaine Abuse|Cocaine-Related Disorders Drug: Progesterone|Other: placebo University of Minnesota - Clinical and Translational Science Institute|National Institute on Drug Abuse (NIDA) 2002-07-01 2015-11-16
    NCT01959464 Infertility|Pregnancy Drug: Crinone vaginal progesterone gel|Drug: Placebo vaginal gel Carolinas Healthcare System|Carolinas Medical Center Phase 4 2008-11-01 2014-08-04
    NCT01406197 Preterm Labor Drug: Experimental: Vaginal progesterone|Drug: Experimental: Topical progesterone|Drug: Experimental: Intramuscular progesterone St. Joseph's Hospital and Medical Center, Phoenix 2011-07-01 2016-10-10
    NCT01954966 Nicotine Dependence|Nicotine Withdrawal Drug: Progesterone|Drug: Placebo University of Pennsylvania|National Institute on Drug Abuse (NIDA) Phase 4 2010-11-01 2017-03-20
    NCT02772120 Infertility Drug: Vaginal progesterone gel (Crinone8%)|Drug: Intramuscular Progesterone Brigham and Women's Hospital Phase 4 2016-05-01 2016-05-11
    NCT02338830 Premature Labour Drug: Progesterone Mohamed Sayed Abdelhafez|Mansoura University Phase 4 2012-06-01 2015-01-13
    NCT02913495 Premature Birth Drug: Vaginal Progesterone|Drug: Intramuscular Progesterone Thomas Jefferson University|Baystate Medical Center|George Washington University Phase 4 2016-09-01 2016-12-20
    NCT01081652 Infertility Drug: Micronised Progesterone|Drug: Progesterone Merck KGaA Phase 3 2004-05-01 2014-07-30
    NCT01057511 Postmenopausal Endometrium Drug: Crinone 8%|Drug: Progesterone Peking Union Medical College Hospital|Merck Serono International SA Phase 1|Phase 2 2009-12-01 2012-04-01
    NCT00919919 Endometrial Hyperplasia|Endometrial Cancer Drug: progesterone|Drug: activella Rabin Medical Center|Ferring Pharmaceuticals Phase 2 2009-06-01 2009-06-11
    NCT01249274 Cocaine Abuse|Cocaine Dependence Drug: Progesterone|Other: Placebo Yale University|National Institute on Drug Abuse (NIDA) 2010-08-01 2016-10-19
    NCT03058536 Preterm Birth|Twin Pregnancy With Antenatal Problem Device: Arabin Pessary|Drug: Vaginal Progesterone|Other: Arabin Pessary and Progesterone Mario Henrique Burlacchini de Carvalho|University of Sao Paulo Phase 2|Phase 3 2017-02-21 2017-03-13
    NCT00579553 Infant, Premature|Premature Birth Drug: Intramuscular Progesterone|Drug: Vaginal Progesterone University of Oklahoma 2006-10-01 2014-05-20
    NCT01177904 All Patients Which Show a Gestational Sac in Their Uterus in the First US Are Included in This Study and Randomized. Other: Cease progsterone at 5|Other: control group: progesterone 8 Instituto Valenciano de Infertilidad, IVI VALENCIA Phase 4 2009-01-01 2011-03-16
    NCT00536003 Preterm Delivery|Morbidity|Perinatal Mortality Drug: progesterone|Drug: placebo begoa Martinez de Tejada|Centre Hospitalier Universitaire Vaudois|University Hospital Inselspital, Berne|Basel Women University Hospital|University of Zurich|Kantonsspital Graubuenden|Cantonal Hospital of St. Gallen|Luzerner Kantonsspital|Kantonsspital Winterthur KSW|Besins Laboratory, Belgium|Hospital Bernardino Rivadavia Buenos Aires|Hospital Carlos G. Durand Buenos Aires|CEMIC Buenos Aires|Hospital Donacin Francisco Santojanni Buenos Aires|Hospital Dr. Cosme Argerich Buenos Aires|Hospital Dr. T. Alvarez Buenos Aires|Hospital Italiano de Buenos Aires|Hospital J. M. Penna Buenos Aires|Hospital Materno Infantil Ramn Sard Buenos Aires|Hospital Interzonal Alberto Antranik Eurnekian, provincia Buenos Aires|Hospital Municipal Materno Infantil Comodoro Hugo Cesar Meisner, provincia Buenos Aires|Hospital Comunal de Tigre, provincia Buenos Aires|Hospital Dr. Arturo Oativia, provincia Buenos Aires|Hospital Dr. Carlos Bocalandro, provincia Buenos Aires|Hospital Hroes de Malvinas, provincia Buenos Aires|Hospital Provincial Magdalena V. de Martnez|Hospital Mariano y Luciano de la Vega, provincia Buenos Aires|Hospital Municipal Ostaciana B. de Lavignolle, provincia Buenos Aires|Hospital Materno Infantil de San Isidro, provincia Buenos Aires|Hospital Virgen del Carmen, provincia Buenos Aires|Hospital J. B. Iturraspe, Santa Fe|Hospital Maternidad Nuestra Seora De Las Mercedes, Tucumn|Hospital Materno Infantil San Roque, Entre Ros|Hospital Villa Dolores, Crdoba|University Hospital, Geneva Phase 3 2006-07-01 2012-06-05
    NCT01602679 Female Reproductive Physiology Drug: oral micronized progesterone suspension|Drug: Placebo University of Virginia|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Phase 1 2012-05-01 2017-02-23
    NCT02254577 Infertility Drug: Endometrinplus Progesterone in Oil (PIO)|Drug: Progesterone in Oil (PIO) Only Shady Grove Fertility Reproductive Science Center|Ferring Pharmaceuticals Phase 4 2014-10-01 2016-08-30
    NCT02400021 HIV-1 Infection Drug: Prometrium Mount Sinai Hospital, Canada|CIHR Canadian HIV Trials Network Phase 2 2015-08-01 2015-07-28
    NCT01523483 Preterm Birth Drug: Progesterone|Drug: placebo vaginal capsules University Medical Centre Ljubljana|Slovenian Research Agency 2012-03-01 2015-04-21
    NCT01286246 Obstetric Labor, Premature Drug: Vaginal progesterone|Drug: Placebo University of Calgary Phase 4 2011-01-01 2015-01-07
    NCT00929006 Puberty|Hyperandrogenism Drug: Micronized progesterone suspension|Drug: Placebo University of Virginia|National Institutes of Health (NIH) Phase 1 2008-06-01 2017-02-23

    注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。

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